Liposomal Luteolin

$97.30

Samples can be purchased directly

Specification:98%(HPLC)

Quantity: 100g

Shipping costs included

SKU: EVH-220412 Category:

Description

Premium Liposomal Luteolin Powder (Enhanced Bioavailability Grade)

Specification: Luteolin Content ≥ 10.0% / 20.0% (Custom load factors available)

Carrier Matrix: Natural Non-GMO Sunflower Phosphatidylcholine (PC)

Average Particle Size: 100 nm – 200 nm (Dynamic Light Scattering verified)

Appearance: Light yellow to yellow, fine, free-flowing powder

CAS Number (Active Luteolin): 491-70-3

Technical Overview & Liposomal Delivery Infrastructure

Natural Luteolin is a powerful crystalline flavonoid extracted from premium botanical sources (such as Sophora japonica or Citrus aurantium). However, in industrial formulation development, raw Luteolin presents severe formatting challenges due to its highly hydrophobic (water-insoluble) nature, crystalline aggregation, and poor localized absorption kinetics within target biological systems.

      [ Hydrophobic Luteolin Core ] 
                   │
                   ▼  (Advanced High-Pressure Homogenization)
     ╔═════════════════════════════╗
     ║  ● ● ● Phospholipid ● ● ●   ║  <-- Hydrophilic Outer Shell
     ║ █░░░░░░░░░░░░░░░░░░░░░░░░█ ║
     ║ █░░  [ Luteolin Core ]  ░░█ ║  <-- Lipophilic Core Protection
     ║ █░░░░░░░░░░░░░░░░░░░░░░░░█ ║
     ║  ● ● ● Phospholipid ● ● ●   ║
     ╚═════════════════════════════╝

Our Liposomal Luteolin addresses these molecular limitations through advanced nano-encapsulation technology. Utilizing a premium lipid matrix derived from sunflower phosphatidylcholine, the active luteolin molecules are structurally embedded within the lipophilic core of a phospholipid bilayer vesicle. This structural configuration transforms a traditionally challenging bioflavonoid into a highly stable, water-dispersible, and biologically optimized raw material designed for premium nutraceutical applications.

Comprehensive Technical Specifications (Typical COA)

To ensure strict compliance with global procurement standards and Google Ads transparency guidelines, our standard quality control parameters are fully detailed below:

Test Item Specification Standard Test Method
Active Luteolin Content ≥ 10.0% (or ≥ 20.0% Grade) HPLC
Encapsulation Efficiency ≥ 85.0% Ultrafiltration – HPLC
Average Vesicle Particle Size 100nm – 200nm Dynamic Light Scattering (DLS)
Polydispersity Index (PDI) < 0.25 (Highly Uniform) Laser Diffraction
Appearance Light yellow free-flowing powder Visual
Water Dispersibility Forms stable colloidal suspension Visual
Loss on Drying ≤ 4.0% Vacuum Drying Oven
Bulk Density 0.40 g/ml – 0.60 g/ml USP <616>
Heavy Metals (as Pb) ≤ 10.0 ppm ICP-MS
Lead (Pb) ≤ 1.0 ppm ICP-MS
Arsenic (As) ≤ 1.0 ppm ICP-MS
Total Plate Count ≤ 1,000 cfu/g USP <61>
Yeast & Mold ≤ 100 cfu/g USP <61>
Pathogenic Bacteria Negative USP <62>

Industrial & Formulation Performance Advantages

When evaluating ingredients for large-scale supplement manufacturing, Liposomal Luteolin delivers unmatched operational and structural benefits over standard plant extracts:

1. Complete Hydrophilic Transformation for Liquid Matrixes

Raw luteolin powder precipitates instantly in aqueous environments, making it unusable for liquid products. Our liposomal formulation features a hydrophilic outer shell that allows the particles to disperse completely and uniformly in water. It creates a stable, long-lasting colloidal system with zero gritty sedimentation, making it ideal for advanced ready-to-drink (RTD) beverages and liquid wellness formulas.

2. Enhanced Systemic Protection & Cellular Kinetics

The phospholipid bilayer structures behave as a protective molecular shield. It guards the inner luteolin molecules against premature enzymatic degradation and pH fluctuations in the upper digestive tract. Furthermore, because the liposomal vesicle structurally mimics natural cellular membranes, it facilitates optimal passive transport and endocytosis pathways, significantly augmenting cellular absorption kinetics without relying on high input doses.

3. Superior Mechanical Flowability & Processing Stability

Our specialized Spray-Drying and Micro-encapsulation process turns liquid liposomes into a highly stable powder. Unlike standard hygroscopic plant extracts that clump easily, Liposomal Luteolin features an optimized particle size distribution that resists moisture absorption and flows smoothly. This ensures exceptional performance during high-speed capsule filling and direct-compression tableting operations.

Manufacturing Protocol & Supply Chain Integrity

Our processing facility utilizes cutting-edge pharmaceutical-grade engineering to guarantee the structural uniformity of every batch:

  • High-Pressure Homogenization: We avoid harsh chemical solvents during vesicle formation, relying entirely on physical shear forces and pure aqueous parameters to assemble the lipid bilayer.

  • Premium Excipient Selection: We use only non-GMO, allergen-free sunflower lecithin, ensuring complete freedom from soy-derived residues.

  • Global Certifications: Our production fully complies with cGMP, ISO 9001:2015, ISO 22000, HACCP, Kosher, and Halal standards. Full documentation support—including Particle Size Analysis Reports, MSDS, and Non-GMO Statements—is provided with every order.

B2B Application Matrix & Bulk Packaging

Liposomal Luteolin Powder is a versatile, high-tier active ingredient engineered for diverse commercial formats:

  • Advanced Nutraceuticals: Perfect for premium anti-aging, cognitive support, and metabolic wellness capsules or tablets.

  • Functional Powder Blends: Easily blended into premium dry-mix formulations, meal replacements, and longevity wellness powders.

  • Liquid Fortification Systems: Highly suited for liquid-filled hard capsules, softgel oil suspensions, and functional beverage shots.

Standard Bulk Packaging: 25kg/Fibre Drum (Double-lined with protective, moisture-barrier food-grade PE bags). Small-scale trial lots (1kg/Aluminum foil bag) are available upon request for R&D evaluation, pilot batch testing, and analytical verification.

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