High-Purity Calcium L-Threonate (Premium Food & Supplement Grade)

Specification: Elemental Calcium ≥ 13.0% | L-Threonic Acid Base ≥ 85.0%

Appearance: White to off-white, odorless, crystalline powder

Molecular Formula: C₈H₁₄CaO₁₀

CAS Number: 70753-61-6

Regulatory Compliance: USP / FCC / Enterprise Standard (Non-GMO, Allergen-Free)

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Product Identification & Molecular Structure

Calcium L-Threonate is a highly specialized, bio-optimized organic mineral compound. It is synthesized through the precise aqueous reaction of L-threonic acid—a key physiological metabolite of Ascorbic Acid (Vitamin C)—with a high-purity calcium source.

Unlike conventional inorganic salts, the structural framework of Calcium L-Threonate enables specific metabolic pathways that dramatically improve active transport kinetics, making it a premier active ingredient for top-tier joint-support and mineral-fortification formulations worldwide.

Comprehensive Technical Specifications (Typical Certificate of Analysis)

To guarantee full transparency for international procurement QA/QC workflows and to ensure compliance with global regulatory compliance standards, every production batch adheres to the following parameters:

Analysis Item	Specification Standard	Test Method
Assay (Calcium L-Threonate)	≥ 98.0%	HPLC / Titration
Elemental Calcium Content	13.0% – 14.5%	ICP-OES
Specific Rotation [α]D20	+14.0° to +18.0°	Polarimetry
pH (1% Aqueous Solution)	6.0 – 7.5	pH Meter
Loss on Drying	≤ 1.0%	Vacuum Drying (105°C)
Heavy Metals (as Pb)	≤ 10.0 ppm	Atomic Absorption
Lead (Pb)	≤ 0.5 ppm	ICP-MS
Arsenic (As)	≤ 0.5 ppm	ICP-MS
Cadmium (Cd)	≤ 0.2 ppm	ICP-MS
Mercury (Hg)	≤ 0.1 ppm	ICP-MS
Total Plate Count	≤ 1,000 cfu/g	USP <61>
Yeast & Mold	≤ 100 cfu/g	USP <61>
Coliforms / Salmonella	Negative in 10g / 25g	USP <62>

Verified Formulation & Industrial Advantages

When integrated into commercial scale supplement manufacturing, Calcium L-Threonate addresses key physical and biochemical constraints inherent to older generation mineral sources:

1. Passive Diffusion & Active Transport Synergies

Traditional calcium options require structural breakdown via gastric acids and heavily depend on Vitamin D3-mediated active transport channels. Calcium L-Threonate bypasses these systemic limitations. Because it utilizes the unique cellular uptake pathways of the L-threonate metabolite, it exhibits a significantly higher passive diffusion rate through mucosal layers, achieving exceptional metabolic bioavailability without relying on localized hormonal factors.

2. High Mechanical Stability & Formulation Uniformity

Our optimized crystallization process yields a powder with excellent bulk density (0.50g/ml – 0.70g/ml) and narrow particle size distribution (100% passing through 80 mesh). This specific physical profile offers essential technical benefits:

• Direct Compression (DC) Compatibility: Excellent flowability reduces the need for heavy binding excipients in high-speed tableting operations.

• Agglomeration Resistance: Prevents moisture absorption and clumping in dry-mix protein powders or functional meal replacements.

3. Absolute Gastrointestinal Neutrality

Free calcium ions derived from inorganic salts regularly trigger localized chemical irritation, leading to bloating or digestive discomfort for the end consumer. Calcium L-Threonate maintains an extraordinarily low dissociation constant within the upper digestive tract. It remains chemically non-reactive and highly soluble throughout a broad pH spectrum, ensuring full structural comfort and product satisfaction.

Manufacturing Protocol & Quality Certifications

Our advanced chemical synthesis plant operates strictly under global current Good Manufacturing Practices (cGMP) and total quality management frameworks:

• Advanced Aqueous Synthesis: Zero organic solvents are used during the critical chelation and crystallization stages, completely eliminating the risk of volatile residual impurities.

• Full Traceability Matrix: Every single lot is accompanied by a comprehensive documentation package, including batch records, full ICP-MS elemental profiling, and heavy-metal tracking reports.

• Validated Industrial Audits: Fully certified under ISO 9001:2015, ISO 22000, HACCP, Kosher, and Halal. Complete compliance documentation—including Non-Irradiation Statements, BSE/TSE-Free Certificates, and Material Safety Data Sheets (MSDS)—is standard with every supply agreement.

B2B Application Matrix & Packaging

Calcium L-Threonate is highly versatile and serves as a vital raw material across multiple market sectors:

• Premium Nutraceuticals: Designed for high-speed encapsulation, clean-label tableting, and softgel suspensions.

• Functional Food Systems: Perfect for blending into dairy alternatives (almond, oat, and soy milks) where clear solubility and a neutral flavor profile are mandatory.

• Beverage Fortification: Fully soluble in liquid formulations without creating cloudiness, gritty sedimentation, or altered mouthfeel.

Standard Commercial Packaging: 25kg/Fibre Drum lined with food-grade double polyethylene inner bags. Small-scale sample sizes (1kg/Aluminum foil bag) are available for R&D testing, pilot-batch validation, and pre-production evaluation.

B2B DECLARATION:
This product is intended for business‑to‑business (B2B) trade only – including manufacturing, formulation, and industrial processing. Not for direct retail or consumer sale. All buyers represent that they purchase as a commercial entity for further processing or incorporation into finished products. No medical or therapeutic claims are made or implied.

Compliance note: This page describes a food/ingredient raw material. No disease treatment, cure, or unsubstantiated health claims are made. Traditional references are for informational context only.